Major Histocompatibility Complex (mhc) - Biotechnology

Relevant Publications

Evolutionary variation in gene conversion at the avian MHC is explained by fluctuating selection, gene copy numbers and life history.

Issue Release: 2024

HLA Genes: A Hallmark of Functional Genetic Variation and Complex Evolution.

Issue Release: 2024

Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn\'s Disease.

Issue Release: 2024

CREB1 promotes expression of immune checkpoint HLA-E leading to immune escape in multiple myeloma.

Issue Release: 2024

Activation of Wnt/β-catenin signal induces DCs to differentiate into immune tolerant regDCs in septic mice.

Issue Release: 2024

Epigenetic regulation of major histocompatibility complexes in gastrointestinal malignancies and the potential for clinical interception.

Issue Release: 2024

Lung influenza virus-specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells.

Issue Release: 2024

The systemic cellular immune response against allogeneic mesenchymal stem cells is influenced by inflammation, differentiation and MHC compatibility: study in the horse.

Issue Release: 2024

Soluble Fibrinogen-Like Protein 2 Downregulation and Th17/Treg Imbalance in a Taurocholate-Induced Murine Experimental Model of Severe Acute Pancreatitis.

Issue Release: 2024

An integrated database of experimentally validated major histocompatibility complex epitopes for antigen-specific cancer therapy.

Issue Release: 2024

Improved Immunotherapy Outcomes via Cuproptosis Upregulation of HLA-DRA Expression: Promoting the Aggregation of CD4 and CD8T Lymphocytes in Clear Cell Renal Cell Carcinoma.

Issue Release: 2024

Expression and function of the major histocompatibility complex (MHC) class I chain-related A (MICA)*010 in NK cell killing activity.

Issue Release: 2024

Moderate Genetic Diversity of MHC Genes in an Isolated Small Population of Black-and-White Snub-Nosed Monkeys ().

Issue Release: 2024

Targeting the MHC-I endosomal-lysosomal trafficking pathway in cancer: From mechanism to immunotherapy.

Issue Release: 2024

Anti-CTLA-4 treatment suppresses hepatocellular carcinoma growth through Th1-mediated cell cycle arrest and apoptosis.

Issue Release: 2024

Strengths and limitations of web servers for the modeling of TCRpMHC complexes.

Issue Release: 2024

Correlated evolution of oxidative physiology and MHC-based immunosurveillance in birds.

Issue Release: 2024

Possible Shifts in the Genetic Diversity of Red-crowned Cranes () in Hokkaido, Japan: Indications of Continental Gene Flow.

Issue Release: 2024

Key features of the innate immune response is mediated by the immunoproteasome in microglia.

Issue Release: 2024

Single-cell analysis identifies PLK1 as a driver of immunosuppressive tumor microenvironment in LUAD.

Issue Release: 2024

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